Nitric oxide coordinates growth, development, and stress response via histone modification and gene expression

编号 040031203

推送时间 20211011

研究领域 森林培育 

年份 2021 

类型 期刊 

语种 英语

标题 Nitric oxide coordinates growth, development, and stress response via histone modification and gene expression

来源期刊 Plant Physiology

期 第312期

发表时间 20210518

关键词 nitric oxide;  stress response;  gene expression;  plant physiology;  plant ability; 

摘要 Nitric oxide (NO) is a signaling molecule with multiple regulatory functions in plant physiology and stress response. In addition to direct effects on transcriptional machinery, NO executes its signaling function via epigenetic mechanisms. We report that light intensity-dependent changes in NO correspond to changes in global histone acetylation (H3, H3K9, and H3K9/K14) in Arabidopsis (Arabidopsis thaliana) wild-type leaves, and that this relationship depends on S-nitrosoglutathione reductase and histone deacetylase 6 (HDA6). The activity of HDA6 was sensitive to NO, demonstrating that NO participates in regulation of histone acetylation. Chromatin immunoprecipitation sequencing and RNA-seq analyses revealed that NO participates in the metabolic switch from growth and development to stress response. This coordinating function of NO might be particularly important in plant ability to adapt to a changing environment, and is therefore a promising foundation for mitigating the negative effects of climate change on plant productivity.

服务人员 孙小满

服务院士 尹伟伦

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