A New Polyphenolic Compound from Rubus aleaefolius and Its Inhibitory Activity on Mammalian Cell Cycle at G0／G1 Phase

编号 zgly0000278119

文献类型 期刊论文

文献题名 A New Polyphenolic Compound from Rubus aleaefolius and Its Inhibitory Activity on Mammalian Cell Cycle at G0／G1 Phase

作者 ChengBinCUI  QingChunZHAO 

作者单位 BeijingInstituteofBiomedicine 

母体文献 Chinese Chemical Letters（中国化学快报：英文版） 

年卷期 2002,13(4)

页码 327-330

年份 2002 

分类号 Q946.8  Q952. 

关键词 多酚化合物  悬钩子属植物  哺乳动物  抑制活性  细胞周期 

文摘内容 Rubuphenol (1), a new polyphenolic compound, was isolated together with the known ellagic acid (2) as new cell cycle inhibitors from Rubus aleaefolius Poir. Through a bioassay-guided separation procedure and the structure of 1 was elucidated by spectroscopic method. Compounds 1 and 2 inhibited the cel cycle of tsFT210 cells at the G0/G1 phase respectively with the MIC values of 14.6μM and 10.3μM。