Extraction of betulin from bark of Betula platyphylla by supercritical carbon dioxide extraction

编号 zgly0000306057

文献类型 期刊论文

文献题名 Extraction of betulin from bark of Betula platyphylla by supercritical carbon dioxide extraction

作者 ZHANGYu-hong  YUTao  WANGYang 

作者单位 NortheastForestryUniversity 

母体文献 Journal of Forestry Research（林业研究：英文版） 

年卷期 2003,14(3)

页码 202-204

年份 2003 

分类号 R284.2  Q949.736.2 

关键词 白桦  桦木醇  超临界二氧化碳萃取  提取工艺  萃取条件  药用成分 

文摘内容 Betulin, which is a medicinal pentacyclic triterpene, is abundant in the bark of white birch (Betula platyphlly). The bark of birch was collected at Tayuan Forest Farm of Jiagedaqi, Heilongjiang Province in September 2000. Supercritical fluid extraction (SFE) that is a new separation technology has been used for the processing pharmaceutical and natural products. In this paper, the extraction of betulin from the bark of birch by supercritical CO2 extraction was studied. The authors investigated and analyzed a few parameters such as modifier dosage, extraction pressure and extraction temperature. The optimal extraction conditions showed that the modifier dosage used for per gram bark powder was 1.5 mL, the extraction pressure was at 20 Mpa, and the extraction temperature was at 55 ℃. The velocity of flow of liquid CO2 was at 10 kg/h. The pressure and temperature in separation vessel were at 5.5 Mpa and 50 ℃, respectively。