Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

编号 zgly0000626318

文献类型 期刊论文

文献题名 Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

作者 Chien-yu  CHEN  Yea-huey  CHANG  Da-tian  BAU  Hung-jin  HUANG  Fuu-jen  TSAI  Chang-hai  TSAI  Calvin  YU-chian  CHEN 

作者单位 Laboratory  of  Pharmacoinformatics  and  Nanotechnology  of  Biological  Science  and  Technology  Medical  University  40402  Graduate  Institute  of  Chinese  Medical  Science  Medical  University  40402  Terry  Fox  Cancer  Research  Lab  Medical  University  Hospital  40402  Department  of  Medical  Genetics  and  Medical  Research  Medical  University  Hospital  and  College  of  Chinese  Medicine  Medical  Uni-versity  40402  Department  of  Bioinformatics  University  41354  Department  of  Healthcare  Administration  University  41354  Department  of  Biological  Engineering  and  Center  forCancer  Research  Institute  of  Technology  02139 

母体文献 中国药理学报：英文版 

年卷期 2009(8)

页码 1186-1194

年份 2009 

分类号 Q556.1  S763.421 

关键词 药效分析  抑制剂  磷酸二酯酶  虚拟筛选  多元线性回归  结合位点  传统中药  分子对接