Studies on the Antibacterial Activity of the Extract of Stachytarpheta angustifolia

编号 zgly0000315032

文献类型 期刊论文

文献题名 Studies on the Antibacterial Activity of the Extract of Stachytarpheta angustifolia

作者 YakubuMBello  OdamaLE  NanditaBDe 

作者单位 DepartmentofIntegratedScience 

母体文献 Journal of Nanjing Medical University;南京医科大学学报: 英文版 

年卷期 2003,17(3)

页码 116-121

年份 2003 

分类号 R282.71  R284.1 

关键词 植物药  抗菌活性  有效成分  胆宁酸  皂角苷  石碳酸 

文摘内容 Objective: To investigate the scientific bases for the traditional use of Stachy-tarpheta angustifolia. Methods: In vitro antibacterial activity of the aqueous and ethanol extract of the plant was investigated using the agar cup plate diffusion method. Results: The ethanol extract of the plant showed antibacterial activity against Escherichia coli, Streptococcus faecalis, Shigella dysenteriae, Staphylococcus aureus (S.aureus), Salmonella sp., Pseudomonas aeruginosa and Neisseria gonorrhoeae, while the water extract was active against Escherichia coli, Streptococcus faecalis, Shigella dysenteriae, Staphylococcus aureus and. Pseudomonas aeruginosa. The ethanol extract exhibited higher antibacterial activity than the water extract. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the ethanol extract were 0.65mg/ml and 0.85mg/ml, respectively, anainst S.aureus. Treatment of the extract at higher temperature, 60℃ increased the sensitivity of the test organisms to the plant extract. Phytochemical analysis indicated that the plant possesses tannins, saponins as well as phenols. Conclusion: A scientific basis exists that the plant possesses antibacterial activity and it could be a probable source of therapeutic agent。