Decoding the Auxin Matrix: Auxin Biology Through the Eye of the Computer

编号 040038204

推送时间 20230213

研究领域 森林培育 

年份 2022 

类型 期刊 

语种 英语

标题 Decoding the Auxin Matrix: Auxin Biology Through the Eye of the Computer

来源期刊 Annual Review of Plant Biology

期 第382期

发表时间 20230106

关键词 auxin signaling;  polar auxin transport;  development;  evolution; 
bioinformatics;  computational modeling;  synthetic biology; 

摘要 The plant hormone auxin is certainly the most studied developmental regulator in plants. The many functions of auxin during development, from the embryo to the root and shoot construction, are mediated by an ever-growing collection of molecular regulators, with an overwhelming degree of both ubiquity and complexity that we are still far from fully understanding and that biological experiments alone cannot grasp. In this review, we discuss how bioinformatics and computational modeling approaches have helped in recent years to explore this complexity and to push the frontiers of our understanding of auxin biology. We focus on how analysis of massive amounts of genomic data and construction of computational models to simulate auxin-regulated processes at different scales have complemented wet experiments to increase the understanding of how auxin acts in the nucleus to regulate transcription and how auxin movement between cells regulates development at the tissular scale.

服务人员 孙小满

服务院士 尹伟伦

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