Design principles of a minimal auxin response system

编号 040024302

推送时间 20200615

研究领域 森林培育 

年份 2020 

类型 期刊 

语种 英语

标题 Design principles of a minimal auxin response system

来源期刊 Nature Plants

期 第243期

发表时间 20200515

关键词 auxin response system;  land plants;  ARF;  gene expression; 

摘要 Auxin controls numerous growth processes in land plants through a gene expression system that modulates ARF transcription factor activity1,2,3. Gene duplications in families encoding auxin response components have generated tremendous complexity in most land plants, and neofunctionalization enabled various unique response outputs during development1,3,4. However, it is unclear what fundamental biochemical principles underlie this complex response system. By studying the minimal system in Marchantia polymorpha, we derive an intuitive and simple model where a single auxin-dependent A-ARF activates gene expression. It is antagonized by an auxin-independent B-ARF that represses common target genes. The expression patterns of both ARF proteins define developmental zones where auxin response is permitted, quantitatively tuned or prevented. This fundamental design probably represents the ancestral system and formed the basis for inflated, complex systems.

服务人员 孙小满

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