Redox-dependent structural switch and CBF activation confer freezing tolerance in plants

编号 040030502

推送时间 20210823

研究领域 森林培育 

年份 2021 

类型 期刊 

语种 英语

标题 Redox-dependent structural switch and CBF activation confer freezing tolerance in plants

来源期刊 Nature Plants

期 第305期

发表时间 20210621

关键词 freezing tolerance;  CBF;  cold-responsive;  cold tolerant;  cold-mediated redox changes; 

摘要 The activities of cold-responsive C-repeat-binding transcription factors (CBFs) are tightly controlled as they not only induce cold tolerance but also regulate normal plant growth under temperate conditions1,2,3,4. Thioredoxin h2 (Trx-h2)—a cytosolic redox protein identified as an interacting partner of CBF1—is normally anchored to cytoplasmic endomembranes through myristoylation at the second glycine residue5,6. However, after exposure to cold conditions, the demyristoylated Trx-h2 is translocated to the nucleus, where it reduces the oxidized (inactive) CBF oligomers and monomers. The reduced (active) monomers activate cold-regulated gene expression. Thus, in contrast to the Arabidopsis trx-h2 (AT5G39950) null mutant, Trx-h2 overexpression lines are highly cold tolerant. Our findings reveal the mechanism by which cold-mediated redox changes induce the structural switching and functional activation of CBFs, therefore conferring plant cold tolerance.

服务人员 孙小满

服务院士 尹伟伦

PDF文件 浏览全文