Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

编号 020024004

推送时间 20200525

研究领域 林产化工 

年份 2020 

类型 期刊 

语种 英语

标题 Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

来源期刊 Advanced science

期 第240期

发表时间 20190821

关键词 cyborganics;  nanocomposite hydrogels;  nanomaterials;  self‐healing hydrogels;  tissue engineering; 

摘要 Given their durability and long‐term stability, self‐healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility between hydrogel toughness and rapid self‐healing remains unaddressed, and therefore most of the self‐healable hydrogels still face serious challenges within the dynamic and mechanically demanding environment of human organs/tissues. Furthermore, depending on the target tissue, the self‐healing hydrogels must comply with a wide range of properties including electrical, biological, and mechanical. Notably, the incorporation of nanomaterials into double‐network hydrogels is showing great promise as a feasible way to generate self‐healable hydrogels with the above‐mentioned attributes. Here, the recent progress in the development of multifunctional and self‐healable hydrogels for various tissue engineering applications is discussed in detail. Their potential applications within the rapidly expanding areas of bioelectronic hydrogels, cyborganics, and soft robotics are further highlighted.

服务人员 尚玮姣

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