Crosslinking Strategies for 3D Bioprinting of Polymeric Hydrogels

编号 020027203

推送时间 20210104

研究领域 林产化工 

年份 2021 

类型 期刊 

语种 英语

标题 Crosslinking Strategies for 3D Bioprinting of Polymeric Hydrogels

来源期刊 Nano.micro small

期 第272期

发表时间 20200730

关键词 3D bioprinting;  bioinks;  crosslinking strategies;  hydrogel–cell interactions;  tissue engineering; 

摘要 Three‐dimensional (3D) bioprinting has recently advanced as an important tool to produce viable constructs that can be used for regenerative purposes or as tissue models. To develop biomimetic and sustainable 3D constructs, several important processing aspects need to be considered, among which crosslinking is most important for achieving desirable biomechanical stability of printed structures, which is reflected in subsequent behavior and use of these constructs. In this work, crosslinking methods used in 3D bioprinting studies are reviewed, parameters that affect bioink chemistry are discussed, and the potential toward improving crosslinking outcomes and construct performance is highlighted. Furthermore, current challenges and future prospects are discussed. Due to the direct connection between crosslinking methods and properties of 3D bioprinted structures, this Review can provide a basis for developing necessary modifications to the design and manufacturing process of advanced tissue‐like constructs in future.

服务人员 尚玮姣

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