Synthesis and Biological Activity of 6-methyl-4-hydroxy-2-pyrone Derivatives

编号 zgly0001465606

文献类型 期刊论文

文献题名 Synthesis and Biological Activity of 6-methyl-4-hydroxy-2-pyrone Derivatives

作者 Chi Jianguo  Kong Xue  Gao Yongchao  Huang Yujie 

作者单位 Key Laboratory of Applied Microbiology of Shandong Province /Institute of Biology  Shandong Academy of Sciences 

母体文献 Plant Diseases and Pests 

年卷期 2014年04期

年份 2014 

分类号 O621.3  TQ460.1 

关键词 Pyrone  Synthesis  Antifungal activity 

文摘内容 With maleic acid as the raw material,6-methyl-4-hydroxy-2-pyrone,6-methyl-4-alkoxy-2-pyrone and 6-methyl-4-hydroxy-3-acyl-2-pyrone derivatives were obtained via loop closing,O-alkylation and acylation reaction,and antifungal activity was also tested. Structure of products was characterized by1 H NMR and MS,and preliminary biological activity tests showed that some of this series of compounds had good inhibitory activity against Rhizoctonia solani and Fusarium moniliforme Sheld.