Coordinated Transcriptional Regulation by the UV-B Photoreceptor and Multiple Transcription Factors for Plant UV-B Responses

编号 040023501

推送时间 20200420

研究领域 森林培育 

年份 2020 

类型 期刊 

语种 英语

标题 Coordinated Transcriptional Regulation by the UV-B Photoreceptor and Multiple Transcription Factors for Plant UV-B Responses

来源期刊 MOLECULAR PLANT

期 第235期

发表时间 20200229

关键词 UV-B;  UVR8;  MYB13;  transcription factor;  transcriptional regulation; 

摘要 Non-damaging ultraviolet-B (UV-B) light promotes photomorphogenic development and stress acclimation in Arabidopsis through UV-B-specific signal transduction. UV-B irradiation induces monomerization and nuclear translocation of the UV-B photoreceptor UV RESISTANCE LOCUS 8 (UVR8). However, it is not clear how the nuclear localization of UVR8 leads to changes in global gene expression. Here we reveal that nuclear UVR8 governs UV-B responsive transcriptional networks in concert with several previously known transcription factors, including ELONGATED HYPOCOTYL 5 (HY5) and PHYTOCHROME INTERACTING FACTOR 4 (PIF4). Based on our transcriptomic analysis, we identify MYB13 as a novel positive regulator in UV-B-induced cotyledon expansion and stress acclimation. MYB13 is UV-B inducible and is predominantly expressed in the cotyledons. Our results demonstrate that MYB13 protein functions as a transcription factor to regulate the expression of genes involved in auxin response and flavonoid biosynthesis, and directly binds to their promoters. In addition, photoactivated UVR8 interacts with MYB13 in a UV-B dependent manner, and differentially modulates the affinity of MYB13 with its targets. Taken together, our results elucidate the cooperative function of the UV-B photoreceptor UVR8 with various transcription factors in the nucleus to orchestrate the expression of specific sets of downstream genes, and ultimately, mediate plant responses to UV-B light.

服务人员 孙小满

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