Cis-regulatory sequences in plants Their importance, discovery, and future challenges

编号 040033802

推送时间 20220411

研究领域 森林培育 

年份 2022 

类型 期刊 

语种 英语

标题 Cis-regulatory sequences in plants Their importance, discovery, and future challenges

来源期刊 The Plant Cell

期 第338期

发表时间 20211122

关键词 Cis-regulatory sequences DNA;  developmenta;  environmenta plant biology;  crop improvement; 

摘要 The identification and characterization of cis-regulatory DNA sequences and how they function to coordinate responses to developmental and environmental cues is of paramount importance to plant biology. Key to these regulatory processes are cis-regulatory modules (CRMs), which include enhancers and silencers. Despite the extraordinary advances in high-quality sequence assemblies and genome annotations, the identification and understanding of CRMs, and how they regulate gene expression, lag significantly behind. This is especially true for their distinguishing characteristics and activity states. Here, we review the current knowledge on CRMs and breakthrough technologies enabling identification, characterization, and validation of CRMs; we compare the genomic distributions of CRMs with respect to their target genes between different plant species, and discuss the role of transposable elements harboring CRMs in the evolution of gene expression. This is an exciting time to study cis-regulomes in plants; however, significant existing challenges need to be overcome to fully understand and appreciate the role of CRMs in plant biology and in crop improvement.

服务人员 孙小满

服务院士 尹伟伦

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