JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in Arabidopsis

编号 040028901

推送时间 20210503

研究领域 森林培育 

年份 2021 

类型 期刊 

语种 英语

标题 JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in Arabidopsis

来源期刊 Molecular Plant

期 第289期

发表时间 20210302

关键词 Jasmonate;  JA response;  Polycomb proteins;  Polycomb repression;  JAZ proteins;  anther development;  H3K27me3;  LHP1; 

摘要 Jasmonate (JA) regulates various aspects of plant growth and development and stress responses, with prominent roles in male reproductive development and defenses against herbivores and necrotrophic pathogens. JASMONATE-ZIM DOMAIN (JAZ) proteins are key regulators in the JA signaling pathway and function to repress the expression of JA-responsive genes. Here, we show that JAZ proteins directly interact with several chromatin-associated Polycomb proteins to mediate repressive chromatin modifications at part of JA-responsive genes and thus their transcriptional repression in Arabidopsis. Genetic analyses revealed that the developmental defects, including anther and pollen abnormalities resulting from loss or block of JA signaling, were partially rescued by loss of Polycomb protein-mediated chromatin silencing (Polycomb repression). We further found that JAZ-mediated transcriptional repression requires Polycomb proteins at four key regulatory loci in anther and pollen development. Analysis of genome-wide occupancy of a Polycomb factor and transcriptome reprogramming in response to JA reveals that Polycomb repression is involved in the repression of various JA-responsive genes. Taken together, our study reveals an important chromatin-based mechanism for JAZ-mediated transcriptional repression and JA signaling in plants.

服务人员 孙小满

服务院士 尹伟伦

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