Glycosylation of N-Hydroxy-Pipecolic Acid Equilibrates between Systemic Acquired Resistance Response and Plant Growth

编号 040027701

推送时间 20210208

研究领域 森林培育 

年份 2021 

类型 期刊 

语种 英语

标题 Glycosylation of N-Hydroxy-Pipecolic Acid Equilibrates between Systemic Acquired Resistance Response and Plant Growth

来源期刊 Molecular Plant

期 第277期

发表时间 20201229

关键词 N-hydroxy-pipecolic acid;  N-hydroxy-pipecolic acid glycoside;  UDP-glycosyltransferase;  glycosylation;  systemic acquired resistance;  plant growth; 

摘要       N-hydroxy-pipecolic acid (NHP) activates plant systemic acquired resistance (SAR). Enhanced defense responses are typically accompanied by deficiency in plant development and reproduction. Albeit extensive studies of SAR induction, the effect of NHP metabolism on plant growth is presently unexplored. Here, we discovered that NHP glycosylation is a critical factor that fine-tunes the tradeoff between SAR defense and growth. It appears that a UDP-glycosyltransferase (UGT76B1) forming NHP Glycoside (NHPG) controls the NHP to NHPG ratio. The ugt76b1 mutant exhibits enhanced SAR response and an inhibitory effect on plant growth while UGT76B1 overexpression attenuates SAR response, promotes growth and delays senescence. Our results indicate that in the course of SAR, NHP levels are dependent on UGT76B1 function. We further increased the complexity of the SAR-associated network by suggesting that upon pathogen attack, UGT76B1-mediated NHP glycosylation forms a ‘hand brake’ on NHP accumulation by attenuating the positive regulation of NHP biosynthesis pathway genes. In addition, we provide evidence that NHP glycosylation through UGT76B1 in the local side is significant in terms of fine-tuning the SAR response. Thus, engineering immunity through manipulating the NHP / NHPG ratio is a promising method to balance growth and defense response in crop species.

服务人员 孙小满

PDF文件 浏览全文