An RNA thermoswitch regulates daytime growth in Arabidopsis

编号 040024003

推送时间 20200525

研究领域 森林培育 

年份 2020 

类型 期刊 

语种 英语

标题 An RNA thermoswitch regulates daytime growth in Arabidopsis

来源期刊 Nature Plants

期 第240期

发表时间 20200413

关键词 bHLH transcription factor;  PIF7;  plant growth;  temperature;  RNA thermoswitch; 

摘要 Temperature is a major environmental cue affecting plant growth and development. Plants often experience higher temperatures in the context of a 24?h day–night cycle, with temperatures peaking in the middle of the day. Here, we find that the transcript encoding the bHLH transcription factor PIF7 undergoes a direct increase in translation in response to warmer temperature. Diurnal expression of PIF7 transcript gates this response, allowing PIF7 protein to quickly accumulate in response to warm daytime temperature. Enhanced PIF7 protein levels directly activate the thermomorphogenesis pathway by inducing the transcription of key genes such as the auxin biosynthetic gene YUCCA8, and are necessary for thermomorphogenesis to occur under warm cycling daytime temperatures. The temperature-dependent translational enhancement of PIF7 messenger RNA is mediated by the formation of an RNA hairpin within its 5′ untranslated region, which adopts an alternative conformation at higher temperature, leading to increased protein synthesis. We identified similar hairpin sequences that control translation in additional transcripts including WRKY22 and the key heat shock regulator HSFA2, suggesting that this is a conserved mechanism enabling plants to respond and adapt rapidly to high temperatures.

服务人员 孙小满

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