RAF22, ABI1 and OST1 form a dynamic interactive network that optimizes plant growth and responses to drought stress in Arabidopsis

编号 040035804

推送时间 20220829

研究领域 森林培育 

年份 2022 

类型 期刊 

语种 英语

标题 RAF22, ABI1 and OST1 form a dynamic interactive network that optimizes plant growth and responses to drought stress in Arabidopsis

来源期刊 Molecular Plant

期 第358期

发表时间 20220605

关键词 ABA signaling;  RAF22;  ABI1;  OST1;  phosphorylation; 

摘要 Plants adapt to their ever-changing environment via both positive and negative signals induced by environmental stimuli. Drought stress, for instance, induces the accumulation of the plant hormone abscisic acid (ABA), triggering ABA signaling transduction. However, the molecular mechanisms for switching between plant growth promotion and response to stress are still poorly understood. Here, we report that the RAF (Rapidly Accelerated Fibrosarcoma)-LIKE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 22 (RAF22) in Arabidopsis thaliana physically interacts with ABA INSENSITIVE 1 (ABI1) and phosphorylates the ABI1 Ser416 residue to enhance its phosphatase activity. Moreover, ABI1 can also enhance the activity of RAF22 through dephosphorylation, thereby reciprocally inhibiting ABA signaling and promoting the maintenance of plant growth under normal conditions. Under drought stress, however, the ABA-activated OPEN STOMATA1 (OST1) phosphorylates the Ser81 residue of RAF22 and inhibits its kinase activity, thus restraining its enhancement on ABI1 activity. Our study thus reveals that RAF22, ABI1 and OST1 form a dynamic regulation network that plays crucial roles in optimizing plant growth and environmental adaptation under drought stress.

服务人员 孙小满

服务院士 尹伟伦

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