The blue-light receptor CRY1 interacts with GID1 and DELLA proteins to repress GA signaling during photomorphogenesis in Arabidopsis

编号 040029404

推送时间 20210607

研究领域 森林培育 

年份 2021 

类型 期刊 

语种 英语

标题 The blue-light receptor CRY1 interacts with GID1 and DELLA proteins to repress GA signaling during photomorphogenesis in Arabidopsis

来源期刊 Molecular Plant

期 第294期

发表时间 20210507

关键词 Cryptochrome 1;  blue light;  gibberellic acid;  GID1;  DELLA proteins;  Arabidopsis; 

摘要 Light is a critical environmental cue that regulates a variety of diverse plant developmental processes. Cryptochrome 1 (CRY1) is the major photoreceptor mediating blue light-dependent photomorphogenic responses, such as inhibition of hypocotyl elongation. Gibberellin (GA) participates in repressing photomorphogenesis and promotes hypocotyl elongation. However, the antagonistic interaction between blue light and GA is not well understood. Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Data from our in vitro and in vivo biochemical analyses demonstrate that CRY1 physically interacts with GA receptors—GA INSENSITIVE DWARF 1 proteins (GID1s)—and DELLAs in a blue light-dependent manner. Furthermore, we show that CRY1 inhibits the association between GID1s and DELLAs. Genetically, CRY1 antagonizes the function of GID1s to repress the expression of cell elongation-related genes and hypocotyl elongation. Taken together, our findings demonstrate that CRY1 signals by stabilizing DELLAs through binding and inactivating GID1s and provide new insight into the mechanism by which blue light antagonizes the function of GA in photomorphogenesis.

服务人员 孙小满

服务院士 尹伟伦

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