Towards a hierarchical gene regulatory network underlying somatic embryogenesis

编号 040037405

推送时间 20221219

研究领域 森林培育 

年份 2022 

类型 期刊 

语种 英语

标题 Towards a hierarchical gene regulatory network underlying somatic embryogenesis

来源期刊 Trends in Plant Science

期 第374期

发表时间 20221201

关键词 arabidopsis;  chromatin accessibility;  hierarchical gene regulatory network;  regeneration;  somatic embryogenesis;  totipotency.; 

摘要 Genome-editing technologies have advanced in recent years but designing future crops remains limited by current methods of improving somatic embryogenesis (SE) capacity. In this Opinion, we provide an update on the molecular event by which the phytohormone auxin promotes the acquisition of plant cell totipotency through evoking massive changes in transcriptome and chromatin accessibility. We propose that the chromatin states and individual totipotency-related transcription factors (TFs) from disparate gene families organize into a hierarchical gene regulatory network underlying SE. We conclude with a discussion of the practical paths to probe the cellular origin of the somatic embryo and the epigenetic landscape of the totipotent cell state in the era of single-cell genomics.

服务人员 孙小满

服务院士 尹伟伦

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