Extrachromosomal circular DNA: A neglected nucleic acid molecule in plants

编号 040036501

推送时间 20221017

研究领域 森林培育 

年份 2022 

类型 期刊 

语种 英语

标题 Extrachromosomal circular DNA: A neglected nucleic acid molecule in plants

来源期刊 Current Opinion in
Plant Biology

期 第365期

发表时间 20220721

关键词 eccDNA;  eccDNA sequencing;  Transposable elements;  Environmental adaptation; 

摘要 Throughout the years, most plant genomic studies were focused on nuclear chromosomes. Extrachromosomal circular DNA (eccDNA) has largely been neglected for decades since its discovery in 1965. While initial research showed that eccDNAs can originate from highly repetitive sequences, recent findings show that many regions of the genome can contribute to the eccDNA pool. Currently, the biological functions of eccDNAs, if any, are a mystery but recent studies have indicated that they can be regulated by different genomic loci and contribute to stress response and adaptation. In this review, we outline current relevant technological developments facilitating eccDNA identification and the latest discoveries about eccDNAs in plants. Finally, we explore the probable functions and future research directions that could be undertaken with respect to different eccDNA sources.

服务人员 孙小满

服务院士 尹伟伦

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